Exploration of the Genetic Architecture of Idiopathic Generalized Epilepsies
نویسندگان
چکیده
منابع مشابه
Epidemiology of idiopathic generalized epilepsies.
Idiopathic generalized epilepsies (IGEs) are a relatively new category of disorders defined by strict clinical and electroencephalogram (EEG) features proposed by the International League Against Epilepsy (ILAE) classification of epileptic syndromes. IGEs are usually easy to diagnose when clinical and EEG data are collected, but epilepsy is not synonymous with epileptic syndrome. So far, IGEs a...
متن کاملGenetic Causes of Generalized Epilepsies.
Generalized epilepsies, particularly the idiopathic or genetic generalized epilepsies (GGEs), represent some of the most common epilepsies. Clinical genetic data including family studies and twin studies provide compelling evidence for a prominent genetic impact. The first decade of the 21st century was marked by progress in understanding the basic biology of generalized epilepsies including ge...
متن کاملis interictal eeg correlated with the seizure type in idiopathic (genetic) generalized epilepsies?
how to cite this article: asadi-pooya aa, emami m. is interictal eeg correlated with the seizure type in idiopathic (genetic) generalized epilepsies? iran j child neurol 2012;6(2): 25-28. objective we investigated the correlation between different interictal eeg abnormalities observed in patients with idiopathic (genetic) generalized epilepsies (iges) and their seizure types. material & metho...
متن کاملThe profusion of genotypes and phenotypes in "idiopathic" generalized epilepsies.
The myriad genetic associations with idiopathic (primary) generalized epilepsies (IGE) are challenging to both researchers and caregivers. There are numerous mutations, among them voltagegated sodium, potassium, and calcium channels and ligand-gated GABA receptors. A variety of mutations may produce similar phenotypes, while, equally troublesome, single mutations may produce a range of phenotyp...
متن کاملEEG-fMRI of idiopathic and secondarily generalized epilepsies.
We used simultaneous EEG and functional MRI (EEG-fMRI) to study generalized spike wave activity (GSW) in idiopathic and secondary generalized epilepsy (SGE). Recent studies have demonstrated thalamic and cortical fMRI signal changes in association with GSW in idiopathic generalized epilepsy (IGE). We report on a large cohort of patients that included both IGE and SGE, and give a functional inte...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2006
ISSN: 0013-9580,1528-1167
DOI: 10.1111/j.1528-1167.2006.00677.x